SubCulture_Logo_Paper.svg__PID:3676e878-2d05-42a0-8dfb-e042e85e9b9f

for Your
Unique Self

Well-Being-icon.png__PID:2b9ac1f5-3345-4cb1-b61a-43c2679accdc
Bloat-icon.png__PID:9ac1f533-450c-41b6-9a43-c2679accdcec
Digestion-icon.png__PID:c1f53345-0cb1-461a-83c2-679accdcec87
Immune-icon.png__PID:f533450c-b1b6-4a43-8267-9accdcec8731
Regularity-icon.png__PID:33450cb1-b61a-43c2-a79a-ccdcec8731e7
Urinary-icon.png__PID:450cb1b6-1a43-4267-9acc-dcec8731e782
Vaginal-icon.png__PID:0cb1b61a-43c2-479a-8cdc-ec8731e78233
Well-Being-icon.png__PID:2b9ac1f5-3345-4cb1-b61a-43c2679accdc
Bloat-icon.png__PID:9ac1f533-450c-41b6-9a43-c2679accdcec
Digestion-icon.png__PID:c1f53345-0cb1-461a-83c2-679accdcec87
Immune-icon.png__PID:f533450c-b1b6-4a43-8267-9accdcec8731
Regularity-icon.png__PID:33450cb1-b61a-43c2-a79a-ccdcec8731e7
Urinary-icon.png__PID:450cb1b6-1a43-4267-9acc-dcec8731e782
Vaginal-icon.png__PID:0cb1b61a-43c2-479a-8cdc-ec8731e78233
Well-Being-icon.png__PID:2b9ac1f5-3345-4cb1-b61a-43c2679accdc
Bloat-icon.png__PID:9ac1f533-450c-41b6-9a43-c2679accdcec
Digestion-icon.png__PID:c1f53345-0cb1-461a-83c2-679accdcec87
Immune-icon.png__PID:f533450c-b1b6-4a43-8267-9accdcec8731
Regularity-icon.png__PID:33450cb1-b61a-43c2-a79a-ccdcec8731e7
Urinary-icon.png__PID:450cb1b6-1a43-4267-9acc-dcec8731e782
Vaginal-icon.png__PID:0cb1b61a-43c2-479a-8cdc-ec8731e78233

Get ready for a cultural awakening, with probiotics formulated to help you thrive. Great health starts from within, beginning with a balanced microbiome. SubCulture™ Probiotics deliver clinically studied strains to promote digestion, regularity and immune health.* With formulas especially for Bloat, Mood or Women.* Embrace the culture within!

SubHero_Photo3UpLockup_v2.jpg__PID:afb07b0a-f9ed-4793-9971-26067a768f74
SubCulture_Lockup.svg__PID:451ac12a-ecd2-4a2a-9457-47976558c36d

Whether it’s boosting digestion, promoting regularity or giving your immune health a little kick, SubCulture™ Probiotics have you covered.*

SubCulture™ for Women

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Vaginal*

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Digestion*

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Immune*

Probiotics for Women's Urinary and Vaginal Health*

Taking control of your sexual health? We’re so here for that! SubCulture™ for Women delivers clinically studied probiotic strains for women’s urinary and vaginal health, bolstered with foundational probiotics.*

With extensively studied strains featured in several women’s health clinical trials: Lactobacillus rhamnosus GR-1™, Lactobacillus reuteri RC-14™, Saccharomyces boulardii and Bacillus subtilis DE111.*

Learn More
$ 38.24
$ 44.99
Learn More

SubCulture™ for Mood

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Well-Being*

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Digestion*

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Immune*

Feel-Good Probiotics & Post-Biotics with L-Theanine*

Gut feelings? They’re real – and so is the gut-brain connection. SubCulture™ for Mood blends probiotics and post-biotics clinically studied to support mental stress and improve the quality and depth of sleep, with L-Theanine and additional foundational probiotic strains.* 

With ingredients specifically chosen for this feel-good formula: Probiotics, plus the clinically studied post-biotic Lactobacillus gasseri CP2305, help mental stress and improve sleep.* L-Theanine is an amino acid shown to help promote happiness and relaxation while also reducing stress.*

$ 38.24
$ 44.99
Learn More

$XX.xx   $XX.xx

SubCulture™ for Bloat

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Digestion*

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Immune*

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Regularity*

Bloat-Busting Probiotics*

Not today, belly. SubCulture™ for Bloat delivers a blend of clinically studied probiotics to help reduce occasional gas and bloating, with foundational strains to promote digestion, regularity and immune health (and that oh-so-good feeling of a flatter tummy).* This bloat-busting formula also includes specially chosen strains: Bacillus subtilis BS50, Bacillus coagulans, Lactobacillus acidophilus DDS-1 and Bacillus subtilis DE111®.*

$ 38.24
$ 44.99
Learn More

$XX.xx   $XX.xx

The SubCulture™ Story

At Enzymedica, we help make great health easier for everyone. 

We created SubCulture™ Probiotics to help you embrace what’s good in you – and feel your best inside and out. Taking care of your gut by nourishing your microbiome with probiotics is key to a healthier, more vibrant life.

Since 1998, we’ve found the best ingredients on the planet, validated them with the latest science and formulated clean, effective products made without compromise.

Along the way, we try to make a difference in the world by investing in people and planet initiatives that support our values and our legacy.

Read on to learn about probiotics and each targeted formula.

Read about ProbioticsLearn about ProductsRead SubCulture™ Blog

Along the way, we try to make a difference in the world by investing in people and planet initiatives that support our values and our legacy.

People-and-Planet-24.png__PID:f59d62d1-093e-4edf-87d3-f303d6fab4cc

SubCulture
for Women

Probiotics for women’s urinary and vaginal health*

With extensively studied Lactobacillus rhamnosus GR-1™, Lactobacillus reuteri RC-14™, Saccharomyces boulardii and Bacillus subtilis DE 111*

Foundational strains to promote digestion, regularity and immune health*

Why We Chose These Strains

With hundreds of strains out there, consider each of these formulas to be an expertly curated collection of probiotics. We did all the research so you don’t have to know the difference between Lactobacillus rhamnosus and reuteri.

Each capsule includes ingredients specifically chosen to support women’s health, including extensively studied strains featured in several clinical trials: Lactobacillus rhamnosus GR-1™, Lactobacillus reuteri RC-14™, Saccharomyces boulardii and Bacillus subtilis DE111.*

women-why-we-chose-these-strains-square.png__PID:bc29efd9-c52f-4f73-9e12-9a03dbde7450
Why Women Need Their Own Probiotics

In your body as in life, it’s all about balance. Even the strongest and most resilient among us gets thrown off balance sometimes. Urinary tract and vaginal imbalances can happen at the most inopportune of times – weekend getaways, during final exams, work trips, the onset of new relationships, marathon training, etc.

How can you find your balance? Think of your microbiome the same way you would your yoga practice, for example. If you want to stay strong and steady in tree pose or headstand, it needs to be a habit – you don’t quit after the first wobble. You practice to build strength and find ease. Making probiotics a habit is even easier. Simply take one capsule daily, to cover your bases and find your balance.

women-why-women-need-their-own-probiotics.png__PID:07e8f8b6-bbcf-4ea8-9f01-407cddecea6e
Why Those Old Home Remedies Don’t Work

The rules of dating – and taking care of our sexual health – have changed a lot in the last few decades. Why are we still relying on advice that’s so last century? Drink cranberry juice for urinary health? It’s partially true: This tart, tannin-rich fruit does contain a substance that makes the lining of the bladder and urinary tract slippery. However, you’d need to drink a full cup of mouth-puckering, unsweetened juice twice a day (for weeks).

Adding baking soda to water? It lacks research and could lead to occasional digestive discomforts since you’re neutralizing stomach acid.

SubCulture™ offers an easier way – one that’ll help you thrive as your unique, best self!

women-why-old-remedies-dont-work.png__PID:ce61f394-1c7b-472b-8c23-8df30a58adf5

SubCulture
for Mood

Feel-good probiotics & post-biotics with L-Theanine*

Includes the clinically studied post-biotic Lactobacillus gasseri CP2305

Foundational strains to promote digestion, regularity and immune health*

Why We Chose These Ingredients

Each delayed-release capsule includes ingredients specifically chosen for this feel-good formula: Probiotics, plus the clinically studied post-biotic Lactobacillus gasseri CP2305, help mental stress and improve the quality and depth of sleep.* L-Theanine is an amino acid shown to help promote happiness and relaxation and reduce stress.*

Mood-why-we-chose-these-ingredients.png__PID:4307f7e1-687d-457e-a3b3-7b81b15e3a8c
What is the Gut-Brain Connection?

Ever have a “gut feeling”? Science has proven that there is a gut-brain axis that is a two-way street, with messages coming and going from the immune, nervous, endocrine and other systems. Your digestive tract is lined with hundreds of millions of neurons. This “gut brain” is your enteric nervous system. Thanks to all those neurons and your vagus nerve, it’s on speed dial with your actual brain and central nervous system. About half of your dopamine and 95% of your serotonin and are supplied by your gut bacteria.

That connection means that what you do for your gut impacts the brain — and vice-versa. Probiotics help maintain a healthy balance of gut bacteria and keep the brain and gut connected.

mood-what-is-teh-gun-brain-connection.png__PID:9756a58e-5d02-422d-934a-5d9b3c5959ba
Why L-Theanine?

L-Theanine is an amino acid naturally found in certain types of teas. It has been shown to help promote happiness and relaxation and reduce stress.* The amino acid is believed to promote healthy levels of feel-good hormones like dopamine and serotonin.*

mood-why-L-Theanine.png__PID:776aed6b-b643-490e-8ab9-790c2315f44a
What is Lactobacillus gasseri CP2305?

The clinically studied post-biotic Lactobacillus gasseri CP2305 helps mental stress and improve the quality and depth of sleep.*

mood-what-is-lactobacillus-gasseri.png__PID:711c1b3d-7e55-4f19-89c6-d5a7f688d7ff

SubCulture
for Bloat

Bloat-busting probiotics*

Clinically studied probiotics to help reduce occasional gas and bloating*

Foundational strains to promote digestion, regularity and immune health*

Why Does Bloat Happen?

Occasional bloating happens for a couple of reasons: Water retention and gas produced in the intestines. Probiotics can offer support for the latter. Ideally, when we digest food, we chew it thoroughly and produce adequate digestive enzymes to break it down without any slowdowns. But if partially undigested food starts to reach the end of the line or if it lingers too long, it can ferment in the large intestine, leading to gas – especially if there aren’t enough good bacteria there to offer support.

bloat-why-does-bloat-happen-square.png__PID:c96d9448-6840-42ca-8129-6957910790cc
Why Choose Probiotics Vs. Enzymes?

Probiotics and enzymes go together like peas and carrots – and there’s no need to choose just one! They can work together in the digestive system. Enzymes break down the food, and probiotics ensure the gut has enough healthy bacteria for optimal digestion. You take one or both!

Bloat-Why-Choose-Probiotics-Vs-pn.png__PID:d03a73ce-40d4-43ff-996c-159d7d2e5d8d
Why Do Women Seem to Have More Bloat?

No, it’s not in your head! Certain occasional GI complaints (including those connected to stress) are more common in women, especially as we age. The American College of Gastroenterology has found:

  • Women experience slower gastric emptying (a reason why more women deal with occasional nausea and bloating) and release less gastric acid than men.
  • Women are more likely to be “super tasters” and are more sensitive to GI tract stimulation.
  • Throughout most of their lifespan, women’s large intestines empty more slowly (and are longer than men’s).
  • Women’s anal sphincters squeeze with less pressure but their esophageal sphincters squeeze with more force, especially after drinking fluids.

Why? When it comes to occasional digestive issues, researchers think that differences in nerve cells within women’s GI tracts are responsible.

bloat-why-does-women-seem-to-have-more-bloat.png__PID:02734360-ea32-4d0a-8dae-173552785ce3

Probiotics 101

What are Probiotics?

Probiotics are the beneficial bacteria that live in your gut. They are living things — mostly bacteria. They are found throughout your digestive tract, especially in your intestines. Probiotics help to keep the bad bacteria that enter your body in check, and they assist in promoting a well-functioning digestive system. Certain probiotics even produce those helpful digestive enzymes that break down your foods. Your gut is home to not only your digestion, but also much of your immune system. Probiotics have benefits that extend beyond the digestive system.*

Probiotics101_What are Probiotics_Square.jpg__PID:5925cd99-d03a-4961-8859-2c50172dcc40

Probiotics 101

What are Probiotics?

Some of the benefits of probiotics include:
Checkmark-Small.svg__PID:3a47c9b7-45a4-4250-83aa-1bfd135c04b2

Reducing occasional gas and bloating*

Checkmark-Small.svg__PID:3a47c9b7-45a4-4250-83aa-1bfd135c04b2

Healthy digestion and regularity*

Checkmark-Small.svg__PID:3a47c9b7-45a4-4250-83aa-1bfd135c04b2

Immune health*

Checkmark-Small.svg__PID:3a47c9b7-45a4-4250-83aa-1bfd135c04b2

Urinary and vaginal health*

Checkmark-Small.svg__PID:3a47c9b7-45a4-4250-83aa-1bfd135c04b2

A balanced microbiome*

Checkmark-Small.svg__PID:3a47c9b7-45a4-4250-83aa-1bfd135c04b2

Foundational support*

Checkmark-Small.svg__PID:3a47c9b7-45a4-4250-83aa-1bfd135c04b2

Well-being and mood*

Probiotics101_What are Probiotics pt2_Square.jpg__PID:615925cd-99d0-4a89-a188-592c50172dcc

Probiotics 101

And What Do Probiotics Really Do?

In short, probiotics are tasked with the 3 Cs in your microbiome: crowd, create and communicate.
Crowd
Icon-Crowd.svg__PID:e263f63a-2fd7-42aa-af3d-b386264ffcae

Balance is a game of numbers. The good ones need to crowd out the unwanted/bad ones, then adhere to the lining of your gut. Think of it like a game of musical chairs in the GI tract!

Create
Icon-Create.svg__PID:7f27195f-9a0e-4ae0-8f26-da27f9f35922

As probiotics do their work and naturally die off, they create post-biotics. These are beneficial by-products (short-chain fatty acids, enzymes, vitamins, neurotransmitters, etc.) that have their own health benefits.

Communicate
Icon-Communicate.svg__PID:47e7dbec-1d90-40a0-9283-acc7d766c430

These bacteria are alive – and they are active! They get involved in communication between the gut and the brain (via the vagus nerve and neurotransmitters), immune system (via cytokines and T cells) and more.

Probiotics101_And What Do Probiotics Really Do_Square.jpg__PID:531e540b-d21c-496a-bd8d-c96831da6824

Probiotics 101

What is the Microbiome?

The microbiome is the “mini-ecosystem” of microbes living everywhere throughout your body, including your skin, vagina, urinary tract, eyes, mouth and gut. Most of the bacteria are helpful (symbiotic) or at least not harmful (non-pathogenic). While the microbiome contains all the bacteria in and on your body, several health benefits have been linked to the bacteria in your gut specifically, and this is what most people are referring to when they talk about all the good the microbiome can do for you.

These benefits include:
What-is-microbiome-list.png__PID:e913823a-959b-425a-9239-04813e57249e
The goal of the microbiome is balance, so the good bacteria can do its important work.
Probiotics101_What is the Microbiome__Square.jpg__PID:25cd99d0-3a89-4188-992c-50172dcc4004

Probiotics 101

Why Food Isn’t Enough

Certain foods do provide probiotics. These include: kefir, yogurt, sauerkraut, kimchi, miso, tempeh, kombucha and some types of cheese. However, due to cooking, storage or food preservation methods, the probiotics are often partially or completely killed off before you eat them. These foods still deliver health benefits, as dead probiotics are known as post-biotics. These compounds possess their own beneficial qualities! They also offer plenty of nutrition.

But, if you’re looking to support a specific aspect of your health and well-being using probiotics, talk to your health-care provider about choosing a probiotic supplement for women’s health, bloating, mood, digestion, regularity, etc.

Probiotics101_Why Food Isn't Enough_Square.jpg__PID:2938fb8a-1ba9-4761-a6da-b87414e0afd2

A Probiotics Primer

Probiotics

Beneficial bacteria that live in your gut/are consumed as supplements. They are living things — mostly bacteria. They are found throughout your digestive tract, especially in your intestines. Probiotics help to keep the bad bacteria that enters your body in check, and they assist in promoting a well-functioning digestive system. Certain probiotics even produce those helpful digestive enzymes that break down your foods.

Prebiotics

Fermentable fiber that serves as food for probiotics. They are indigestible carbohydrates that are easily metabolized by the microflora in the gut. Prebiotics help maintain digestive health and regularity by feeding probiotics. Good sources of prebiotics include: chicory root, pea fiber, green bananas, cooked and cooled rice and pasta, onions and garlic. While a healthy balanced diet usually provides ample prebiotic fiber, you can also take prebiotics as a supplement.

Post-biotics

Once your probiotics have consumed the prebiotics, it produces beneficial by-products, called post-biotics. They include compounds like vitamins, enzymes and amino acids. Probiotics transform prebiotics into post-biotic compounds, including short-chain fatty acids that benefit your health. Dead probiotics are also post-biotics!

Synbiotics

This refers to the combination of prebiotics and probiotics, since they work together to benefit the host (that’s you!). (Sometimes also called symbiotics.)

Probiotics and Microbiome FAQs

What's a CFU?

A CFU is a colony-forming unit. This represents the number of viable bacteria or yeast cells in a dose that can multiply and form colonies. A CFU number on the bottle indicates the potency of the probiotic supplement. The higher the CFU count, the more live microorganisms are present, typically ranging from millions to billions per dose.

But potency isn’t solely dependent on that number: The effectiveness of probiotics also relies on the specific strains used and their ability to survive through the digestive tract. It's important to choose a product with an appropriate CFU count based on individual health needs.

How do I take SubCulture™?

As with any supplement, follow the instructions on the label. SubCulture™ is a once-daily probiotic capsule. Adults take one capsule daily, with or without food.

Why should I take SubCulture™?

We believe great health starts with healthy digestion. Taking care of your gut – by nourishing your microbiome with probiotics – is key to a healthier, more vibrant life. Why?

Cultural awakenings start from within, and a healthy gut supports not only digestion and regularity but also the immune system, mood, women’s health and more.*

How long do probiotics take to work?

Individual responses vary, so consistency is key when taking probiotics. For best results, it's often recommended to continue for at least a month before evaluating effectiveness.

The time it takes for probiotics to work can vary depending on several factors, including the specific strain of probiotic, the health condition being addressed and an individual’s overall health. You might notice changes in digestive issues within a few days to a couple of weeks, while immune, mood and other areas of health may take longer.

What does SubCulture™ do?

SubCulture™ delivers clinically studied probiotics in formulas designed to help you feel your best, from the inside-out. We start with our core blend of 7 strains for foundational microbiome support. Alive and active, they won’t die off in the bottle – or in your gut. With 50 billion CFU, it covers your bases, promoting digestion, regularity and immune health.*

Is SubCulture™ compatible with my dietary restrictions?

All SubCulture™ products are vegetarian; some are also Kosher. As with all Enzymedica products, our probiotics contain no crustaceans, eggs, fish, gluten, nuts, sesame, shellfish, soy, wheat and artificial colors, fillers or flavors.


Is SubCulture™ safe to take while pregnant or breastfeeding?

Consult with a physician if you are pregnant or nursing, taking medications or have a medical condition.

What’s inside SubCulture™

There are literally hundreds of clinically studied probiotic strains out there. We chose the ones in SubCulture™ because they are proven to stay alive and active! We’ve done the quality testing to ensure that what’s on the label is what’s in the bottle. These probiotics will stay potent, so you can take care of yourself.

And what’s not

All SubCulture™ products are vegetarian; some are also Kosher. As with all Enzymedica products, our probiotics contain no crustaceans, eggs, fish, gluten, nuts, sesame, shellfish, soy, wheat and artificial colors, fillers or flavors.

SubCulture-painting.jpg__PID:99ab9e68-8b5a-444c-80b2-167b9a3bd17d

What’s inside SubCulture™

There are literally hundreds of clinically studied probiotic strains out there. We chose the ones in SubCulture™ because they are proven to stay alive and active! We’ve done the quality testing to ensure that what’s on the label is what’s in the bottle. These probiotics will stay potent, so you can take care of yourself.

And what’s not

All SubCulture™ products are vegetarian; some are also Kosher. As with all Enzymedica products, our probiotics contain no crustaceans, eggs, fish, gluten, nuts, sesame, shellfish, soy, wheat and artificial colors, fillers or flavors.

SubCulture_Bottles_3UpLockup.png__PID:cfe53162-660e-49f3-b5cd-571c18924987
Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Sourced with the best ingredients on the planet

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Validated using the latest human clinical studies

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

For clean, effective products made without compromise

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Non-GMO Project verified

Shop All SubCulture™ Probiotics
SubCulture_Bottles_3UpLockup.png__PID:cfe53162-660e-49f3-b5cd-571c18924987
Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Sourced with the best ingredients on the planet

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Validated using the latest human clinical studies

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

For clean, effective products made without compromise

Checkmark-Small.svg__PID:e29423f0-09c9-4aeb-a670-513785d9ba9d

Non-GMO Project verified

Vegetarian.png__PID:b5d811be-4648-443d-aa42-02efe5a75dd8
Vegetarian
Gluten-Free.png__PID:ea28efff-36b5-4811-be46-48643d6a4202
Gluten Free
Soy-Free.png__PID:36b5d811-be46-4864-bd6a-4202efe5a75d
Soy Free
Dairy-Free.png__PID:02ea28ef-ff36-45d8-91be-4648643d6a42
Dairy Free
No-artificial-colors.png__PID:efff36b5-d811-4e46-8864-3d6a4202efe5
No artificial colors
No-artifical-fillers.png__PID:28efff36-b5d8-41be-8648-643d6a4202ef
No artificial fillers
Non-GMO-white.png__PID:ff36b5d8-11be-4648-a43d-6a4202efe5a7
Asset 15 3x-8.png__PID:dc04b833-08ad-4157-912f-e4bf5be47a9b
Asset 14 3x-8.png__PID:75dc04b8-3308-4d91-9791-2fe4bf5be47a
Asset 11 3x-8.png__PID:4a14064e-43d0-4326-8c1c-b4ac910ccc95